British hospital workers are exhausted as wards fill with COVID-19 patients. Meanwhile, controversy surrounds the government's decision to offer single vaccine doses. We hear from the medical frontline, and from an eminent immunologist.

Also in the programme: new US president Joe Biden launches his pandemic policy; and how can people look after their mental health during lockdown?

(Picture: vaccination in the Northeast of England. Credit: PA)

Joe Biden has been sworn in as the 46th US president, ending one of the most dramatic political transitions in American history. Kamala Harris became the first woman - and the first person of colour - to be made vice president.

Also in the programme: Leaders from around the world have congratulated President Biden; and China has imposed sanctions on more than twenty members of the outgoing Trump administration.

(Photo: Father Leo O' Donovan talks to President-elect Joe Biden during the inauguration of Joe Biden as US President in Washington. Credit: EPA).

President Trump has bid farewell to the American people in a brief video message where he also asked the US to pray for the incoming administration of Joe Biden, while the US Senate Republican leader, Mitch McConnell, accused Trump of provoking the assault on the Capitol by his supporters two weeks ago.

Also in the programme: We asked a spokesman for the Ugandan government why the US ambassador was prevented from visiting the opposition leader Bobi Wine; and the US State Department amounts what China is doing with his Muslim population in Xinjiang as “genocide”.

(Photo: U.S. President Donald Trump departs after speaking about the 2020 U.S. presidential election. Credit: Reuters).

Alexei Navalny has been detained after returning to Moscow for the first time since he was poisoned last year in a nerve agent attack he blames on the Russian president, Vladimir Putin. A judge in Moscow has ruled he must stay in custody for at least thirty days and another hearing next week will determine if he should complete a prison sentence for alleged embezzlement. The US and European Union have led calls for Mr Navalny to be freed.

Also in the programme: worries about the availability of food in the Tigray region of Ethiopia; and how will Somalia manage the battle against jihadists after US troops withdraw?

Picture: Alexei Navalny escorted out of a police station near Moscow; Credit: EPA

Kremlin critic Alexei Navalny has been detained by police at passport control after flying back to Russia - five months after he was almost killed in a nerve agent attack. We hear the latest on events in Moscow.

Also on the programme: Dissecting the complex legacy of American music producer Phil Spector, who has died aged 81 while serving a prison sentence for murder. And do cloth masks offer as much protection against Covid-19 as we think?

(Photo: Russian opposition leader Alexei Navalny is seen on board a plane before the departure for the Russian capital Moscow at an airport in Berlin, Germany January 17, 2021. REUTERS/Polina Ivanova)

Uganda’s veteran leader Yoweri Museveni has declared himself the winner of the presidential election and called it the most fraud-free vote in the country’s history. But rival candidate Bobi Wine tells Newshour he believes the contest to be “the most fraudulent election in the history of Uganda”.

Also in the programme: As Germany’s governing party elects a new leader - seen by some as Chancellor Angela Merkel's likely successor - what does the future hold for Germany’s place in Europe and the world in the post-Merkel era?

And how a team of Nepalese climbers have made history by becoming the first to reach the summit of K2 in winter.

(Image: A supporter of incumbent Ugandan Presdent Yoveri Museveni and Uganda’s National Resistance Movement (NRM) celebrates in the streets of Kampala, Uganda, 16 January 2021. Credit: EPA/STR)